Efficient. Ethical. Experienced.
Now part of Versiti Clinical Trial Services.
Pearl IRB provides independent IRB review services that help protect research participants while helping sponsors, CROs, investigators and institutions move studies forward with clarity, quality and confidence.
Get Started
Follow our easy guide to submit your study to begin the review process.
Fees
Obtain our Fee Schedule for your next single or multi-site study.
Pearl IRB and Salus IRB Merger Announcement
Effective January 1, 2027, Pearl IRB will merge with Salus IRB as part of Versiti Clinical Trial Solutions (VCTS).
By bringing our teams together, we will continue providing ethical regulatory review and personalized service to support your research.
Key Dates and Deadlines
- November 24: Last day to submit new protocols or major protocol amendments through Pearl IRB Manager.
- December 8: Deadline to download and save backup copies of documents from Pearl IRB Manager.
- December 8: Final day to submit continuing reviews that are due and minor protocol amendments.
- December 9–14: Pearl IRB Manager will be temporarily unavailable while data migration takes place.
- December 15: The new, integrated Salus IRB Manager platform will be available for all submissions.
What does this mean for your studies?
No action is required at this time. Existing studies will automatically transfer to Salus IRB’s IRB Manager system. We will email clients additional information as the transition progresses. Please refer to the Pearl IRB + Salus IRB Merger FAQ for additional support.
Planning an upcoming study or have questions about how we can support your research?
Nimble
Exceptionally quick turnaround times to accelerate your clinical research.
Ethical
AAHRPP accredited. Committed to high quality research and strengthening human subject protection programs.

Independent REVIEW. INTEGRATED SUPPORT.
Pearl IRB remains focused on ethical, high-quality independent review while giving clients access to the broader Versiti Clinical Trial Services network when additional regulatory, quality, CRO, lab or biologistics support is needed.

SOCIAL AND BEHAVIORAL RESEARCH EXPERTISE
Pearl IRB brings deep experience reviewing social, behavioral, educational and qualitative research. Our board understands that these studies often involve different risks, methods and participant considerations than traditional clinical trials — and that the review should fit the research.
From expedited and exempt determinations to Certificates of Confidentiality, funding requirements and protections for vulnerable populations, our team provides thoughtful, practical review that supports ethical research without forcing a clinical-trial framework where it does not belong.
