Researchers from Princeton University, California Institute of Technology, Harvard School of Public Health and the University of Cambridge are currently testing a new trial design called “two-by-two,” which could potentially provide a better link to a patient’s behavior and the treatment benefits. The major change from the standard double-blind trial would be sharing with the patient their chances of getting the experimental drug. This would allow for a closer analysis of how a patient’s reaction and behavior may influence efficacy. Click here to read more about the new design and how it could alter results.